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For example, higher GPX3 and PPAR expression has been reported during disease onset, with a subsequent decrease with advancing disease [19, 21]

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GSTM2 modulates size and number of LDs in HepG2 cells To further investigate the potential regulatory mechanism, we generated a GSTM2 -knockdown stable cell line (shGSTM2-HepG2) that expressed less GSTM2 mRNA and protein than control cells (shNC-HepG2) (Fig