The HPLC trace for incubation with complex 1 showed one and the same signal at 1.72 min after 1, 3 and 5 min, which was assigned to the GSSG molecule
doi: 10.1155/2016/2853045, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 358
Therefore, CHAC1 drives ferroptosis via two convergent mechanisms: the direct depletion of glutathione and the indirect facilitation of mitochondrial ROS production, thereby coupling sustained metabolic activity to ferroptotic cell death under cysteine limitation
Screening of studies was based on analyzing titles and abstracts, and only articles published in indexed journals and written in English were considered
Antioxidant defense : Neutralises free radical activity and reduces oxidative stress markers at the cellular level
[unverified no linkable source] Vendor-assigned expiry and temperature-stability handling conventions for lyophilised peptides