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CIT significantly improved endothelial function, forearm microvascular reactivity (TOI indices), plasma arginine levels, and calf muscle strength (both absolute and body-weightnormalized) compared with placebo

The key to both diagnosis and patient management lies in determining whether the pancytopenia results from a production disorder, a consumption disorder, or a combination of both [1]

Most commercial product is sold and used as oral capsules/powder rather than reconstituted

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