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Combined treatment of Met and L-car upregulated UCP1 expression and enhanced the activity of mitochondria in SFA-exposed adipocytes (Figure 4c)
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15 Upon arrival, MSCs encounter elevated concentrations of growth factors such as transforming growth factor-beta (TGF-), bone morphogenetic proteins (BMPs), and fibroblast growth factors (FGFs), which bind to their respective receptors and initiate a series of intracellular cascades that orchestrate chondrogenesis at the transcriptional and epigenetic levels
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