(12) Stefan M, et al
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Minimizing and managing side effects Proactive strategies reduce the likelihood of side effects and help manage any that occur
Bokhove, M
Antioxidants can remove the free radicals intermediates by oxidizing themselves so that they are often reducing agents such as poly-phenols, tocopherols, carotenes, vitamin A, ubiquinols, thiols, ascorbic acid, and others (Sies, 1997)
Excessive iron promotes hydroxyl radical (OH) generation via the Fenton reaction, thereby exacerbating lipid peroxidation and oxidative injury, which in turn facilitates A aggregation, tau hyperphosphorylation, and neuronal degeneration (Pei et al., 2025