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Its stability and resistance to degradation in the gastrointestinal tract make it a unique subject for both systemic and oral administration models

BPC-157 interacts with the nitric oxide (NO) system in a context-dependent manner, counteracting both NO-synthase inhibition and NO excess

Obesity, defined as a body mass index (BMI) of greater than 30, 1 is an established risk factor for many of the most common types of cancer

However, some peptides are more stable at slightly acidic pH values

doi: 10.1146/annurev-immunol-032713-120231 57 Almeida-da-SilvaCLCSavioLEBCoutinho-SilvaROjciusDM