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Metabolism 120, 154780

RPE is particularly prone to lipid peroxidation owing to its persistent phagocytosis of photoreceptor outer segments

If a substance or method is found to meet two of three criteria (enhances performance, poses a threat to athlete health, violates the spirit of sport), then it could be considered for placement on the List

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This results in the intended effect of helping individuals feel full with smaller meals, but patients often also experience another effect of a slow GI system constipation