Winzeler B et al (2020) Effects of glucagon-like peptide-1 receptor agonists on fluid intake in healthy volunteers
By maintaining elevated (but physiologically normal) GH levels through Tesamorelin, the stack may offer meaningful protection against muscle wasting during the caloric deficit that Retatrutide induces
Some patients remain at lower doses longer if results are already strong
No significant statistical difference between patients on/not on GLP-1 agonists regarding smoking, antidepressant use, and age, however, GLP-1 agonists use was associated with gender, BMI, diet, and exercise
It's important to note that NHS provision of Mounjaro for weight management follows NICE technology appraisal guidance and is typically available through specialist weight management services, subject to local commissioning decisions
It is to underline that intellectual disabilities raise relevant ethical concerns in the bariatric treatment of adolescents with PWS and require an accurate preoperative analysis of psychological, social, and ethical aspects to adequately support patients and parents, and the long-term monitoring of the surgical outcome [109]