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Increasing water consumption to at least 8-10 glasses daily during the first month often eliminates this preventable cause

Inoue M, Taketani N, Sato T, Nakajima H

Upon initial removal from the fridge, make a note of this date on the pen or vial, or maintain a record on your calendar to monitor how many days it has been out of the fridge

Copper complexes can be sensitive to Light exposure Moisture and humidity Elevated temperatures and temperature cycling Repeated freeze thaw cycles when in solution If these are not controlled, the actual material in the vial can change over time