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USA 100 , 1220112206 (2003)

which can be as small as 50 nanometers to permeate the lipid bilayer of cells and improve bioavailability

Therefore, it may be difficult to differentiate whether the BH 4 -induced improvements in endothelial dysfunction are either due to recoupling of eNOS or due to the antioxidant properties of BH 4 itself

doi:10.1016/j.nicl.2023.103503

10.1007/s10753-010-9249-5 75 LuG.PanY.KayoumuA.ZhangL.YinT.TongZ.et al (2017a)