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These supplements support heart health and can reduce the risk of adverse events associated with diabetes and GLP-1 medications

It is found that shikonin can stimulate RIPK1 and RIPK3-dependent necrosis and directly promote the up-regulation of DAMPs through autophagy, in which ROS accumulation and NF-B pathway activation may be the main mechanisms of cell necrotizing apoptosis (121)

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Specialist supplements such as DHEA, high-dose myo-inositol, or NAC may be appropriate, but should be discussed with a clinician particularly DHEA, which is only indicated for diminished ovarian reserve