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The viral infection could also cause rapid T lymphocytopenia with functional impairment of T cells, which may onset OxS, pro-inflammatory state, cytokine production, and apoptosis 166,167

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Importantly, the bioactive metabolites of curcumin not curcumin itself are responsible for the effect

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In Drosophila, Chchd2 knockout increases the degradation of OPA1 by peptidase YME1L ( c stabilization, thereby prohibiting cells from apoptosis (Oka et al., 2008)

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