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Melatonin Melatonin, a hormone synthesized primarily by the pineal gland and locally in skin cells, plays a critical role in protecting melanocytes from oxidative stress by acting as a potent antioxidant and modulating cellular defense mechanisms 196

Step 3: Discontinue 5-HTP Taper 5-HTP over one week rather than stopping abruptly to avoid rebound irritability

it depends on your research protocol and preferred dosing volume

Unlike older growth hormone secretagogues that spike cortisol and prolactin, Ipamorelin triggers GH release through the ghrelin receptor without the hormonal noise