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Compounded medications discussed in this article are not FDA-approved finished drug products and are not reviewed by FDA for safety, effectiveness, or quality before marketing

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The Akt/PKB signalling pathway regulates numerous cellular processes in the brain including neurogenesis, neuronal differentiation, and synaptic plasticity [137,138,139]

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Based on data from the Phase 2 randomised controlled trial published in the New England Journal of Medicine in June 2023, nausea was reported as one of the most common adverse events among participants receiving retatrutide