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The above reaction is catalyzed by acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3)

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In addition to short stature, the developmental delay and cognitive disability are typical features which tend to worsen over time, leading to an autism-like phenotype, including self-mutilation behaviors, skin picking, learning problems, irritability, and compulsive behaviors [26]