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Thus, they demonstrated that Prx2 prevents metHb aggregation, and, probably acts as a chaperone for the denatured Hb [96]

2021 Dec;11(12):4045-4054

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R 4-OH catechol estrogens that are not methylated by COMT can be oxidized to quinones that generate reactive oxygen species and form DNA adducts, a mechanism implicated in estrogen-dependent cancers