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Nonparametric Mann-Whitney U test or Wilcoxon matched-paired signed rank test was performed if data were not normally distributed

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An increase in BBB permeability is commonly observed via enhanced accumulation of blood-derived proteins in the brains of post-mortem AD patients [101] and supported by the reduction of tight junction proteins [102]

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Glutathione and other antioxidants may help with chronic pain issues because they can reduce inflammation in the body