(2011, December 20)
Most recently, AAV9-mediated SLC52A2 gene replacement normalized FMN/FAD levels, rescued spinal motor neurons and reversed motor deficits when delivered pre-symptomatically, underscoring the feasibility of curative therapy (19)
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14 The use of olive oil as a placebo may mask the beneficial clinical effects of EFAs because an active constituent of olive oil is converted into oleamide, which is known to affect brain function
It functions in conjunction with GPX4 and GSH to inhibit lipid ROS and ferroptosis (60, 61)