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Change in body weight (a) and food intake (b) of 47-wk old male DIO C57BL6/J mice treated daily s.c

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Further details regarding the search strategy, eligibility criteria, reviewing process, and study selection flow diagram are described in the supplementary material

One study found that participants using the medication lost 15-20% of their body weight over 68 weeks when combined with a diet and exercise

The diet groups successfully consumed more vegetables, fruits, nuts, legumes, whole grains, and a greater diversity of vegetables, while eating fewer unhealthy snacks, and less red meat and less chicken