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at Osaka University showed that androgen-stimulated dermal papilla cells from balding scalps produce TGF-beta1, which inhibits keratinocyte growth by roughly 50% (Inui et al., 2002)

The pooled 5-year OS rate, 5-year EFS rate, and LR rate were 49%, 37%, and 38%, respectively

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24 , e13568 (2023)

Understanding these mechanisms helps clinicians provide appropriate counselling and implement preventative strategies