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For instance, treatment with SGLT2 inhibitors results in a decline in long-chain acylcarnitines that parallels improvements in mitochondrial function and correlates with a slower rate of eGFR decline [168], suggesting that these metabolites can serve as sensitive pharmacodynamic biomarkers

in addition to anti-psychotic medication) group in comparison to the placebo group over a 24-week period, but not positive symptoms [7]

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doi: 10.1021/jm900752a