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Insulin has roles in synaptic plasticity, modulating tau phosphorylation, amyloid metabolism, and reducing oxidative stress

10.1002/glia.23755 15 HaoW.TashiroS.HasegawaT.SatoY.KobayashiT.TandoT.et al (2015)

Not a minor dip

Upper arm: Back of the arm, midway between shoulder and elbow

Participants were assessed for urinary 6-sulfatoxymelatonin, a metabolite used as an indirect measure of melatonin production

g i ) Representative whole dorsal striatal images of NPY immunofluorescence from Trkb Penk-WT control ( g ), Trkb Penk-KO mutant injected at 3 M with Gsto2 -shRNA ( h ) or scrambled-shRNA in the striatum ( i ) and analysed at 15 W