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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks (vol 123, pg 1213, 2005)

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According to the Semaglutide Treatment Effect in People with Obesity (STEP) program studies, people with overweight or obesity (without T2DM) who received semaglutide 2.4 mg and underwent lifestyle interventions experienced an average weight reduction of 14.7- 17.4% [116]