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Some patients find evening administration allows them to sleep through periods of nausea, though individual responses vary considerably

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Rajput et al used a conventional liposome for a combination strategy with ISG by developing an ion-sensitive ISG containing donepezil-hydrochloride-loaded liposomes to treat Alzheimers disease

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The optimized system exhibited a high encapsulation efficiency (~96%), nanoscale particle size (~123 nm), and sustained-release profile