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However, successful clinical translation will require a deeper understanding of redox thresholds across cell types, subcellular compartments, and disease stages, as well as strategies to overcome compensatory antioxidant networks and systemic toxicity associated with non-specific redox modulation

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Reduction of Inflammation Chronic inflammation has been shown to be a driving force of aging and many chronic diseases

Gene Rep 20:100666

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Since MTHFR is a polymorphic enzyme (79), the preeclamptic women are broadly observed to be homozygous for MTHFR T/T, MTHFR C677T and A1298C (80), which thus can lead to an increase in Hcy level