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These receptors are expressed in a wide variety of tissues including the gastrointestinal tract, central nervous system (specifically cells of the tuberomammillary nucleus of the hypothalamus), both airway and vascular smooth muscle cells, endothelial cells, chondrocytes, monocytes, neutrophils, dendritic cells, T and B lymphocytes, adrenal medulla, and the cardiovascular and genitourinary systems

N Engl J Med (2022)

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Maybe it's like the Hay Flick limit or who knows what it is, but it makes me wonder if, say we crack that code and we can unlock the possibility to live past this glass ceiling that we seemingly have on our longevity

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This, when applied to human skin, can help explain how omega-3 fatty acids help in hydration of the skin cells