where is glp 1 secreted Glucagon-like peptide–1 (GLP-1) from gut endocrine cells in response to food ingestion and acts as an incretin hormone to potentiate glucose-dependent insulin secretion. ⁠ ⁠ Pharmacological GLP-1 receptor (GLP -1R) activation Discovery, characterization, and clinical development

Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans

Expanding applications: GLP-1s are now being explored beyond metabolic diseases, including liver disease (e.g., MASH/NAFLD), cardiovascular health, sleep apnea, alcohol use disorder, and potentially reducing obesity-related cancer risk

Yes, brain shrinkage (termed cerebral atrophy in the research)

Another current challenge in psychiatry is the validity of categorizing mental conditions into separate diseases

Whole grains such as rolled oats, brown rice, quinoa, whole-grain pasta, etc

Cardiometabolic benefits (improved glucose, blood pressure, lipids) accompany weight loss and promise to reduce long-term disease burdens