Western blot (WB) results revealed a significant increase in the expression of Ki-67 and Lamin B, while the protein levels of P21, P16, and -H2AX decreased following FOXO4-DRI treatment (Figure 4A)
7 Excess iron stimulates the formation of reactive oxygen species (ROS) via the Fenton reaction, oxidizing phospholipids in unsaturated fatty acid acyl tails, thereby initiating lipid peroxidation
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In inflammatory models, cerium oxidequercetin nanocomposites (CeO 2 @QU) effectively scavenged ROS and contributed to the maintenance of redox homeostasis (Wang et al., 2021)
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Neither CJC-1295 nor Ipamorelin is FDA-approved for any therapeutic indication