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Chemokine (C-X-C motif) receptor 4 (CXCR4) expression increases during progression of PCa and is associated with metastatic disease and poor survival [50, 51] CXCR4 selectively binds to stromal cell-derived factor 1 (SDF-1)/ CXCL12, also overexpressed in PC metastatic tissue compared to normal tissues [52]

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750 mcg (0.75 mg) dose in a 10 mg vial: Target 20 units (0.2 mL)

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Giugliano et al., 2021a)