Professor Jens Juul Holst, MD, DMSc, is Professor of Medical Physiology at the University of Copenhagen and Senior Group Leader at the Novo Nordisk Foundation Center for Basic Metabolic Research
GLP-1 medications activate peptide receptors that influence glucose metabolism and appetite, but emerging evidence suggests these drugs may also modulate immune and inflammatory pathwaysa critical consideration for patients with lupus or rheumatoid arthritis
10.2337/db08-0121
A review from the National Institutes of Health documented that, in addition to the traditionally understood benefits of the hormone, this drug class has cardio- and neuroprotective effects, decreases inflammation and apoptosis, and has implications for learning and memory, reward behavior, and palatability. Indeed, GLP-1 research has diversified to include non-alcoholic fatty liver disease, polycystic ovary syndrome, peripheral arterial disease and cardiovascular health, among others
Intravenous Glutathione injections are said to provide better levels in the blood and skin than oral capsules
Notably, growing evidence is building about the efficacy of GLP-1RAs in NAFLD [13]
