How we reviewed this article: Current Version October 03, 2025 Written By John DiBella Fact-checked By Dr
This is a good sign that your treatment is working, even if some symptoms are still improving
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If you want to try this: Get insulin syringes for precise tiny measurements Rotate between different spots (belly, thighs, arms) to avoid damaging tissue Watch for any skin reactions or weird lumps Compare how stable your energy feels versus weekly shots Not All B12 Is Created Equal (Even Though the Labels Look the Same) Heres something thatll make you mad: methylcobalamin, hydroxocobalamin, and cyanocobalamin might all say B12 1000mcg/mL on the label, but they work completely differently in your body
So the term off-label is off here since it does not have current FDA approval
Yes, B12 supplementation is appropriate if deficiency is confirmed, and the MHRA recommends monitoring B12 levels in people on long-term metformin