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The two dominant community concentrations are 2.5 mg/mL (for peptides with wide dose ranges) and 5 mg/mL (for peptides dosed in the 250-500 mcg range)

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In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia