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These symptoms are generally mild to moderate in severity and tend to diminish over time as physiologic adaptation occurs

doi: 10.4088/JCP.13r08905

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The following represents a theoretical ultra-conservative approach based on monotherapy principles: Hypothetical Ultra-Conservative Schedule: This extended 24-week titration period doubles the typical monotherapy escalation timeline , reflecting the complete absence of interaction data and the overlapping side effect profiles

Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: the uncertainties related to market conditions and other factors described more fully in the section entitled Risk Factors in Tizianas Annual Report on Form 20-F for the year ended December 31, 2023, and other periodic reports filed with the Securities and Exchange Commission.The forward-looking statements made in this announcement relate only to events as of the date on which the statements are made

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