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No published RCT validates the combination

I dont believe for one moment that whats going on here is an honest investigation of whether these products should be compounded. Scott Brunner of the Alliance for Pharmacy Compounding said the coming meeting will be the start of a protracted process. Even if the panel votes to make the peptides available, and the FDA agrees, the agency will still have to draft and publish rules on the change, he noted

Dihexa was designed specifically to survive first-pass metabolism better than parent angiotensin IV analogs, but most vendor oral capsule claims are not supported by peer-reviewed pharmacokinetic data in humans

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Two of the most discussed are BPC-157 and TB-500

NICE recommends PDE5 inhibitors (sildenafil, tadalafil) as first-line ED treatment, with success rates of 60-70% and well-characterised safety profiles