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it showed that risk rises with long-term high Lp(a).[ref] Waist-to-hip ratio as a modifying factor for atherosclerosis: A 2025 study involving ~800 people with Lp(a) over 50 mg/dL showed that those with a larger waist-to-hip ratio (more belly fat) were at a much higher risk of atherosclerosis

Significant lower risks were observed in patients with and without a diagnosis of obesity (Fig

And getting it wrong can directly impact how well your medication works over time

On the other hand, GLP-1 RA can reduce epicardial fat and semaglutide 2.4 mg have shown to improve physical function and symptoms in people with HFpEF [93]

Its mechanism central melanocortin receptor activation driving dopaminergic desire pathways is distinct from everything that came before it

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