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The levels of HMGB1 in the mouse serum and cultural medium were determined by using the quantitative HMGB1 ELISA kit (Shanghai Westang Bio-Tech Co., Ltd.), according to manufacturers instructions and standard curves of recombinant HMGB1

Primary prevention of cardiovascular and heart failure events With SGLT2 inhibitors, GLP-1 receptor agonists, and their combination in type 2 diabetes

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To interrogate the mechanisms underlying NRF2-directed regulation of this core gene set, we compared mean promoter (1 kb restricted) ChIP-seq signal in A549 for NRF2, p300, as well as the histone marks H3K4me3 and H3K27ac, which are enriched at promoters and enhancers, respectively