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If lifestyle changes are insufficient, a multimodal treatment strategy will be needed to achieve the requisite blood pressure, lipid profile, and blood glucose control targets

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Researchers also observed a potential increase in epithelialization, a process critical for regenerating the skins outer layer, under these experimental conditions

Recent metanalysis have revealed significant increase in oxidative stress markers such as MDA and a substantial depletion of antioxidants such as catalase, GSH in the blood, and postmortem brain of PD patients compared to healthy controls 25

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Then, through the catalytic action of GR, GSSG is reduced back to GSH, achieving its regeneration and sustained antioxidant effect