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Natural GLP-1 in humans degrades in about two minutes, broken down by enzymes before it can provide therapeutic benefit

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GLP-1 receptor agonists work by mimicking the glucagon-like peptide-1 hormone stimulating insulin release, reducing appetite, and slowing gastric emptying

It could infer that aberrant overexpression of ZIP4 elevates zinc concentrations in PC cells

In contrast, MK-677 is a non-peptide compound with a longer half-life and excellent oral bioavailability