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Together, these complementary mechanisms are hypothesised to have a potentially additive effect on liver fat

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Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress

Bile acids are known to be ligands of the nuclear farnesoid X receptor (FXR) and Takeda G protein-coupled receptor 5 (TGR5), also known as G-protein-coupled bile acid receptor 1 (GPBAR1)