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Patients may prefer troches for convenience, ease of self-administration, and steady systemic effects that support overall tissue regeneration

Puckrin R, Saltiel MP, Reynier P, Azoulay L, Yu OHY, Filion KB

Phase 3 trial results suggest that Novo could take a large part of this market

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Suffered the few side effects ( headaches and feeling sick) thought I would be clever quicken up the process and inject 0.4mg in one go, I have never felt so ill, vomiting the sweats etc for 3 days

Similar results were obtained when APEX2 was expressed in the mitochondrial matrix instead of the cytosol (Extended Data Fig