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Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism

ChangWPrattSAChenTHTuCLMikalaGSchwartzAet alParathyroid cells express dihydropyridine-sensitive cation currents and L-type calcium channel subunits

This hypothesis is supported by observations in murine lupus models of MRL/lpr mice are characterized by the presence of lpr gene, associated with defective Fas (CD95) receptor on the surface of lymphocytes

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It has been shown to modulate nitric oxide and growth factor activity, which enhances blood flow and nutrient delivery to damaged tissue