Further, we demonstrated morphine inhibits PVN Glu neuronal activity through the MOR, which in turn leads to suppression of its tonic NMDA receptor-mediated currents to DMV Ach neurons, and ultimately, the overall hypoactivity of this circuit mediates small intestinal dysfunction
After their release, classical neuropeptides exert their specific actions upon a variety of target cells via G-protein coupled receptors [21, 23]
psychiatric Res
Oxidative stress has been shown to influence sleep regulation through its effects on neurotransmitter systems, particularly those involving GABA and serotonin (Tsermpini et al
These enzymes catalyse the conjugation of reduced glutathione (GSH) to electrophilic and lipophilic compounds, making them more water soluble and easier to eliminate
Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers