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Cardiovascular and mortality outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a meta-analysis with the FREEDOM cardiovascular outcomes trial

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First and second-choice prophylactic treatments (Amitriptyline, Cyproheptadine, Propranolol, Pizotifen) are similar to migraine therapies but the safety profile of these drugs can be questionable as CVS is a functional disorder [6-8]

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In a healthy liver, hepatic lipid metabolism maintains intracellular lipid equilibrium, while controlled lipid oxidation supports hepatic energy metabolism, sustaining normal liver function [314]

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