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SURMOUNT-1 (72-week randomized study, adults without diabetes): tirzepatide produced an average loss of 15.0% (5 mg dose), 19.5% (10 mg dose), and 20.9% (15 mg dose) of body weight, versus 3.1% with placebo, under a similar lifestyle-intervention protocol

Remember, most studies on the efficacy of medications for weight loss require participants to make lifestyle modifications during the study

This includes your primary care physician, endocrinologist, or any healthcare provider managing your diabetes and related health concerns

Digestive Changes and Constipation Constipation is a frequent side effect of GLP-1 medications

Get started with an online consultation and begin working toward your weight loss goals with full understanding of how the medication works in your body over time

The reality is that appetite, satiety, fat burning, and fat storage involve very complex physiological processes that can be affected by a wide variety of factors