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Generally well-tolerated , with few side effects

Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily

This is attributed to its ability to stimulate the production of growth factors, promote angiogenesis (the formation of new blood vessels), and elevate the levels of other proteins that support tissue regeneration

Lancet 390, 15501562

doi: 10.2174/0929867321666140303143455 50 FriedmanA.Galazka-FriedmanJ

Separate application windows prevent pH conflicts and let each active work in optimal conditions