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Within one year of stopping, they regained approximately two-thirds of the weight they had lost
In addition to recording the number of patients that reached the target HbA1c levels, the research team also reported the proportion of patients that lost 5-10% of body weight loss [2]
Their use has significantly increased in recent years as newer agents have been effective for improving glucose control and promoting weight loss, in addition to significant cardiovascular and renal benefits
While genetic testing for GLP-1 receptor sensitivity is not yet standard clinical practice, the research points toward a future where dosing protocols could be personalized based on genetic profiles
JAMA 2021 American Diabetes Association Standards of Care in Diabetes 2024: Obesity and Weight Management FDA: Medications Containing Semaglutide and Tirzepatide Marketed for Type 2 Diabetes or Weight Loss Lincoff AM et al
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