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Raji cells were transiently reverse-transfected with siTNFR1 (50 nM), and the cells were cultured for 72 h

This transmission of information across the TM bundle also enables G proteins to allosterically influence ligand affinity for GPCRs 39

In addition, intraperitoneal injection of MOTS-c has the same effect as aerobic exercise, aerobic exercise and intraperitoneal MOTS-c interventions are beneficial in increasing skeletal muscle fatty acid oxidation and glucose utilization (Yang et al., 2021)

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