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Some specific microenvironment and ecological signals are required to turn on different biosynthetic gene clusters (BGCs), which could be researched by transcriptomics and metabolomics in different environmental assays

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Strikingly, reduced production of IL-21 by CD4 + T cells, and decreased frequency of IFN--expressing CD4 + T cells and CD8 + T cells were observed in the presence of L-Cn ( Figures 3C, D )

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