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Finally, the pathway analysis was performed using ShinyGO v0.80 83 and Reactome 84 to investigate the enriched pathways associated with the significant proteins identified by the Random Forest method and Volcano plots

Patients with poorly controlled diabetes face higher risk than those achieving target HbA1c levels, emphasising the importance of optimal glycaemic management

Glycine has been shown in animal studies to improve insulin sensitivity and reduce inflammation in metabolic syndrome models

2024 Apr 12:1720:464776

Experimental and clinical data suggest that melatonin exerts its anti-inflammatory effects by modulating both pro- and anti-inflammatory cytokines in various pathophysiological situations 73,74