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For most people, the weekly convenience of tirzepatide is a significant practical advantage that directly translates to better adherence over months of treatment

Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics

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We think this could lead to new interventions, such as reducing the glutathione overload through synthesis inhibitors or compounds that can dissipate it. The findings also have implications for potential therapies for lung cancers related to mutations in the KEAP1 gene

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